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Downstream Process Development & Analytical Chemist I Oxford I 40k - 50k (dependent on experience)
Are you an experienced analytical chemist with expertise in HPLC and a passion for developing scalable chemical purification processes? We're recruiting for a Downstream Process Development & Analytical Chemist to join an innovative biotechnology business developing sustainable solutions for the chemical manufacturing industry. This is a unique opportunity to take ownership of downstream process development and reaction analytics, using your expertise to optimise chemical manufacturing processes, troubleshoot analytical challenges and support the development of cutting-edge biocatalytic technologies.
The Role
This is a hands-on laboratory role where you'll become the subject matter expert for HPLC, taking ownership of method development, troubleshooting, instrument maintenance and routine analysis. Alongside this, you'll lead the development of downstream processing (DSP) strategies for small molecule chemical products produced through biomanufacturing. This role focuses on chemical purification and process development rather than protein purification, making it ideal for someone with experience in industrial chemistry or chemical process development.
Working closely with chemists and engineers, you'll generate robust analytical data, develop scalable purification processes and help translate laboratory research into commercially viable manufacturing solutions.
Key Responsibilities
Act as the HPLC specialist, leading method development, troubleshooting, routine analysis, calibration and instrument maintenance.
Develop and validate analytical methods using HPLC, alongside techniques such as NMR and UV-Vis.
Design and optimise downstream processing routes for chemical products generated through biocatalytic manufacturing.
Develop scalable purification processes including extraction, solvent exchange, crystallisation and polishing.
Monitor reaction performance, conversion, selectivity, yield and impurity profiles.
Build robust analytical workflows and maintain high standards of data quality, traceability and reporting.
Investigate analytical and process issues, identifying root causes and implementing improvements.
Collaborate with multidisciplinary teams to support R&D projects and customer programmes while maintaining safe laboratory practices.
About You
We're looking for someone who can demonstrate:
A degree in Chemistry, Analytical Chemistry or a related scientific discipline.
At least three years' industrial experience in analytical chemistry.
Extensive hands-on experience with HPLC, including method development, troubleshooting, maintenance and routine operation.
Experience supporting reaction monitoring and analysing complex chemical reaction mixtures.
Practical experience in downstream processing and purification of small molecule chemicals, ideally within biomanufacturing, chemical manufacturing or process chemistry environments.
An understanding that downstream processing in this role relates to chemical manufacturing rather than protein purification.
Excellent problem-solving, communication and collaboration skills.
Apply
If you're looking to apply your HPLC expertise and downstream processing experience in an innovative organisation developing sustainable technologies for the chemical manufacturing sector, we'd love to hear from you.
Katie Pink at Cranleigh STEM & Sustainability is the retained recruitment partner for all roles at Hydregen. Please direct any queries to Katie only.
About the Company
We are seeking a highly skilled and experienced Analytical Development Manager to join our team. This role is pivotal in providing technical leadership, mentoring, and strategic direction to our Analytical Development team. The successful candidate will play a key role in ensuring the delivery of high-quality analytical development projects while driving efficiency, innovation, and commercial success.
About the Role
As the Analytical Development Manager, you will:
Responsibilities
Qualifications
Essential:
Preferred:
Pay range and compensation package
If you are a driven and experienced professional with a passion for analytical development and team leadership, we encourage you to apply for this exciting opportunity. Join us in our mission to improve public health and well-being through innovative scientific solutions.
Senior Analytical Chemist £up to c70k + Bonus
South, ABJ6748
PERM - ONSITE
An exciting opportunity for an experienced Analytical Scientist to join a global Analytical Centre of Excellence supporting the development of innovative analytical capabilities for next-generation products.
Working within a multidisciplinary Research & Science environment, you will provide technical leadership in routine and advanced analytical testing, method development and data interpretation, delivering high-quality analytical data to support product development, scientific understanding, regulatory submissions and competitor analysis.
This role offers the opportunity to work with state-of-the-art analytical instrumentation whilst collaborating with global scientific teams, external laboratories and academic partners.
Key Responsibilities
Experience & Skills Required
Benefits Competitive salary +bonus + strong pension: Comprehensive benefits package.
Ongoing professional development and learning opportunities.
Full Time. To Apply: Please contact Alison Basson on (phone number removed) / (phone number removed) or apply for ABJ6748 to
Analytical Chemist (Mass Spectroscopy)
Leicestershire (commutable from Leicester, Nottingham and surrounding areas)
Salary - 30,000 - 35,000
12 month fixed term contract
SRG is working with a global manufacturer of petcare products, who research and develop new products for their global portfolio. Based in the Leicestershire area, they have recently started hiring for a new member of their lab team. This is a great opportunity for someone with a background in mass spectroscopy (GC-MS, LC-MS) to grow and develop their skills in a leading company. Applications encouraged from people with industrial experience or PhD in analytical chemistry.
Role Description
Requirements
If you would like to apply for this position, please use the link provided. Alternatively, please email a copy of your CV For more information regarding this position or any others, please call Will on (phone number removed) . If you have a scientific background and this position is not relevant / suitable for you, please feel free to get in touch or visit (url removed) to view our other vacancies.
SRG is the UK's number one recruitment company specialising in the scientific, engineering, clinical, pharmaceutical, food/FMCG, energy & renewables, biotech, chemical and medical device sectors. As scientists ourselves, our specialist sector knowledge and our passion are second to none. It's this combination that makes us different. We're committed to providing outstanding temporary, contract and permanent career opportunities of all levels for our candidates and a comprehensive range of expert strategic recruitment services for our clients.
Guidant, Carbon60, Lorien & SRG - The Impellam Group Portfolio are acting as an Employment Business in relation to this vacancy.
Shift Analytical Chemist
Rotating shift pattern - 4 on (2 days, 2 nights), 4 off
South Yorkshire (commutable from Sheffield, Rotherham, Doncaster and surrounding areas)
Salary - 30,000 - 37,000 (Including shift allowance)
Permanent
SRG is working with a leading manufacturer of speciality metals, alloys and materials. Based in the South Yorkshire area, a vacancy has come up for a member of their analytical laboratory team. This would include a shift pattern working 4 days on, 4 days off, two days and two nights. The role would suit a graduate or experienced chemist with a background in analytical metal testing or a background in metallurgy. Applications encouraged from people who've recently graduated and more experienced chemists
Equal Opportunities & Disability Confident Employer
Benefits: 25 days holiday + holiday purchase scheme, cycle to work scheme, life assurance, healthcare scheme and an onsite gym with support from an employee assistance programme
Role Description
Requirements
If you would like to apply for this position, please use the link provided. Alternatively, please email a copy of your CV to For more information regarding this position or any others, please call Will on (phone number removed). If you have a scientific background and this position is not relevant / suitable for you, please feel free to get in touch or visit (url removed) to view our other vacancies.
SRG is the UK's number one recruitment company specialising in the scientific, engineering, clinical, pharmaceutical, food/FMCG, energy & renewables, biotech, chemical and medical device sectors. As scientists ourselves, our specialist sector knowledge and our passion are second to none. It's this combination that makes us different. We're committed to providing outstanding temporary, contract and permanent career opportunities of all levels for our candidates and a comprehensive range of expert strategic recruitment services for our clients.
Guidant, Carbon60, Lorien & SRG - The Impellam Group Portfolio are acting as an Employment Business in relation to this vacancy.
Senior Development Chemist
We are seeking a Development Chemist to join our client's team. This role is essential for supporting their production processes, resolving technical issues, and driving product development and assisting quality control. I'm looking for someone who enjoys the challenge of new product development!
Day-to-day of the role:
Required Skills & Qualifications:
To apply for the Senior Development Chemists role, please submit your CV, detailing your relevant experience and why you are interested in this role.
Senior ICP-MS Analytical Chemist
Location Bedfordshire
Sector ICP-MS Contract Analytical
Salary Depending on experience c£35,000
Contract Full time and permanent
Our client is a specialist contract testing company that offer laboratory analysis services to the agrochemical industry. Based in Bedford, they are seeking a hard-working and enthusiastic Senior Analytical Chemist to join their environmental and pesticide analysis team on a full-time and permanent basis. If you have prior industry experience in environmental sample analysis using ICP-MS and are looking for a new challenge in a company who can foster a long-term career then please apply.
The Role
This is a role for individuals who have previously worked in an accredited (ISO 17025) analytical testing facility, utilising ICP-MS. As a Senior Analytical Chemist, you will be responsible for:
Skills and Experience Needed
Suitable Applicants will have:
The Package
As an industry leader, our client is offering the chance to be part of a growing organisation on a permanent basis with a competitive salary and benefits package. They are able to offer support throughout your career and help with internal progression.
Senior GC-MS Analytical Chemist
Location Bedfordshire
Sector GC-MS Contract Analytical
Salary Depending on experience £40,000 - £50,000
Contract Full time and permanent
Our client is a specialist contract testing company that offer laboratory analysis services to the agrochemical industry. Based in Bedford, they are seeking a hard-working and enthusiastic Senior Analytical Chemist to join their inorganic analysis team on a full-time and permanent basis. If you have prior industry experience in organic analysis using Gas Chromatography Mass Spectrometry (GC-MS) and are looking for a new challenge in a company who can foster a long-term career then please apply.
The Role
This is a role for individuals who have previously worked in an accredited (ISO 17025) analytical testing facility. As a Senior Analytical Chemist, you will be responsible for:
Skills and Experience Needed
Suitable Applicants will have:
The Package
As an industry leader, our client is offering the chance to be part of a growing organisation on a permanent basis with a competitive salary and benefits package. They are able to offer support throughout your career and help with internal progression.
Senior LC-MS Analytical Chemist
Location Bedfordshire
Sector LC-MS Contract Analytical
Salary Depending on experience £35,000 - £45,000
Contract Full time and permanent
Our client is a specialist contract testing company that offer laboratory analysis services to the agrochemical industry. Based in Bedford, they are seeking a hard-working and enthusiastic Senior Analytical Chemist to join their environmental and pesticide analysis team on a full-time and permanent basis. If you have prior industry experience in organic analysis using Liquid Chromatography Mass Spectrometry (LC-MS) and are looking for a new challenge in a company who can foster a long-term career then please apply.
The Role
This is a role for individuals who have previously worked in an accredited (ISO 17025) analytical testing facility. As a Senior Analytical Chemist, you will be responsible for:
Skills and Experience Needed
Suitable Applicants will have:
The Package
As an industry leader, our client is offering the chance to be part of a growing organisation on a permanent basis with a competitive salary and benefits package. They are able to offer support throughout your career and help with internal progression.
Downstream Process Development Scientist
Permanent Darlington 26,939- 36,000 per annum + attractive benefits
About the Role
CPI is seeking a hands-on Downstream Process Development Scientist to join their bioprocessing team in Darlington on a permanent basis.
This is a practical, lab-based role focused on the design, development, and optimisation of downstream purification processes for advanced biologics. You will play a key role in delivering DSP activities across a range of modalities, including viral vectors and nucleic acid-based products, in a fast-moving and highly experimental environment.
Reporting into the DSP leadership team, will be responsible for running experiments, solving problems, and adapting processes, as projects evolve. This role suits someone who enjoys flexibility, iteration, and scientific creativity rather than rigid, highly constrained environments.
The role is based on-site in Darlington, working as part of an established DSP team of approximately 11 scientists.
What You'll Be Responsible For
Downstream Process Development
Chromatography & Filtration
Analytical & Data Interpretation
Collaboration & Laboratory Operations
About You
You are a practical downstream processing scientist who enjoys being in the lab and is comfortable working in an evolving, sometimes ambiguous research and development environment.
You bring curiosity, adaptability, and a willingness to try different approaches - and you're not phased by processes that aren't fully defined from day one.
You'll bring:
Desirable (but not essential):
Applicants from academia are welcome.
Why Join CPI?
Location & Working Pattern
Guidant, Carbon60, Lorien & SRG - The Impellam Group Portfolio are acting as an Employment Business in relation to this vacancy.
Process Operator
Location: Widnes WA8
Salary 28,000
Shifts: 08:30-17:00
Days: Monday-Friday
Our client is seeking a reliable and motivated Process Operator to join their growing team. This is an excellent opportunity for someone with warehouse experience who is looking to develop their career within a well-established industrial environment, with genuine progression opportunities available.
Key Responsibilities
Requirements
What's on Offer?
If you're looking for a long-term opportunity with excellent earning potential and career growth, we'd love to hear from you.
Apply today to be considered for this exciting Process Operator opportunity.
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